Recurrent postinfectious glomerulonephritis: an unusual evolution compatible with C3 glomerulopathy
نویسندگان
چکیده
منابع مشابه
Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion.
Membranoproliferative glomerulonephritis (MPGN) denotes a general pattern of glomerular injury that is easily recognized by light microscopy. With additional studies, MPGN subgrouping is possible. For example, electron microscopy resolves differences in electron-dense deposition that are classically referred to as MPGN type I (MPGN I), MPGN II, and MPGN III, while immunofluorescence typically d...
متن کاملC3 glomerulopathy
C3 glomerulopathy is a recently defined entity that encompasses a group of kidney diseases caused by abnormal control of complement activation with deposition of complement component C3 in glomeruli leading to variable glomerular inflammation. Before the recognition of the unique pathogenesis of these cases, they were variably classified according to their morphological features. C3 glomerulopa...
متن کاملC3 glomerulopathy: the genetic and clinical findings in dense deposit disease and C3 glomerulonephritis.
C3 glomerulopathy (C3G) defines a group of very rare renal diseases in which dysregulation of the alternative and terminal complement pathways plays a pivotal pathogenic role. Dysregulation is driven by genetic and/or acquired defects, with interindividual variability giving rise to two broad subtypes of C3G-dense deposit disease (DDD) and C3 glomerulonephritis (C3GN). Patient evaluation should...
متن کاملCrescentic C3 glomerulopathy with acquired partial lipodystrophy: An unusual cause of rapidly progressive renal failure.
Complement component C3 glomerulopathy (C3GP) is a recently defined entity characterized by predominant glomerular C3 fragment deposition with absent or scanty immunoglobulin deposition due to abnormal control of complement activation, deposition, or degradation.[1] C3GP is subcategorized morphologically into dense deposit disease (DDD) and C3 glomerulonephritis (C3GN) based on electron microsc...
متن کاملTreating C3 glomerulopathy with eculizumab
BACKGROUND C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with grim prognosis. The complex pathogenesis is just unfolding, and involves acquired as well as inherited dysregulation of the alternative pathway of the complement cascade. Currently, there is no established therapy. Treatment with the C5 complement inhibitor eculizumab may be a therapeutic option. However, due to ra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ Case Reports
سال: 2018
ISSN: 1757-790X
DOI: 10.1136/bcr-2017-222979